Papers from the laboratory
Characterization of the interaction between the Sec61 translocon complex and ppαF using optical tweezers
Luka Robeson, Nathalie Casanova-Morales, Francesca Burgos-Bravo, Hilda M. Alfaro-Valdés, Robert Lesch, Carolina Ramírez-Álvarez, Mauricio Valdivia-Delgado, Marcela Vega, Ricardo A. Matute, Randy Schekman, Christian A. M. Wilson. Protein Science, 33(6), e4996. DOI: 10.1002/pro.4996
Towards the understanding of molecular motors and its relationship with local unfolding
Zahra Alavi, Nathalie Casanova-Morales, Diego Quiroga-Roger, Christian A.M. Wilson. Quarterly Reviews of Biophysics, 57, e7. DOI: 10.1017/S0033583524000052
Bioinformatics, thermodynamics, and mechanical resistance of the FtsZ-ZipA complex of Escherichia coli supports a highly dynamic protein interaction in the divisome
Valentina Carrasco, Camillo Berríos-Pastén, Nicolás Canales, Alexis Órdenes, Christian A.M. Wilson, Octavio Monasterio. BBA General Subjects 1867(12), 2023 DOI: 10.1016/j.bbagen.2023.130471
Effect of temperature and nucleotide on the binding of BiP chaperone to a protein substrate
Maira Rivera, Francesca Burgos-Bravo, Felipe Engelberger, Roi Asor, Miguel Lagos, Maximiliano Figueroa, Philipp Kurura, Cesar Ramirez-Sarmiento, Mauricio Baez, Steven Smith, Christian A.M. Wilson. Protein Science 32(7), e4706. DOI: 10.1002/pro.4706
Temperature dependent mechanical unfolding and refolding of a protein studied by thermo-regulated optical tweezers
Maira Rivera, Are Mjaavatten, Steven Smith, Mauricio Baez, Christian A.M. Wilson. Biophysical Journal 122, 1-9, 2023. DOI: 10.1016/j.bpj.2022.12.034
Post-translational Protein Translocation Through Membranes at the Single Molecule Level (preguntar)
Diego Quiroga-Roger, Hilda M. Alfaro-Valdés and Christian A.M. Wilson Moya. Capítulo en el libro “Single-Molecule Science: From Super-Resolution Microscopy to DNA Mapping and Diagnostics” editado por Krishnarao Appasani & Raghu Kiran Appasani. Cambridge University Press. Páginas 80-93. In press, publication planned for October 2020. (ISBN: 9781108423366)
Determination of Protein-Protein Interactions at the single-molecule level Using Optical Tweezers. Quarterly Reviews of Biophysics.
Wendy N. Sánchez, Luka Robenson, Valentina Carrasco, Nataniel Figueroa Leigh, Francesca Burgos-Bravo, Christian A.M. Wilson, Nathalie Casanova-Morales. Volume 55 , 2022 , e8. DOI: 10.1017/S0033583522000075
Mechanical Properties of Chaperone BiP, the Master Regulator of the Endoplasmic Reticulum
Hilda M. Alfaro-Valdés, Francesca Burgos-Bravo, Nathalie Casanova-Morales, Diego Quiroga‐Roger, Christian A.M. Wilson. IntechOpen DOI: 10.5772/intechopen.82080
Mechanical properties of BiP protein determined by nano-rheology
Nathalie Casanova‐Morales, Diego Quiroga‐Roger, Hilda M. Alfaro‐Valdés, Zahra Alavi, Miguel I.A. Lagos‐Espinoza, Giovanni Zocchi, Christian A.M. Wilson Protein Science. DOI: https://doi.org/10.1002/pro.3432
DNA Staining Method Based on Formazan Precipitation Induced by Blue Light Exposure
Aaron J. Paredes, Hilda M. Alfaro-Valdés, Christian A.M. Wilson. Journal of Visualized Experiments (JoVE). Accepted November 16, 2017 http://www.jove.com/video/56528.
Single molecule force spectroscopy reveals the effect of BiP chaperone on protein folding.
Ramírez, M.P.; Rivera, M.; Quiroga-Roger, D.; Bustamante, A.; Vega, M.; Baez, M.; Puchner, E.M.; Wilson, C.A.M. Protein Science. 26 (7), 1404-1412, 2017. DOI: 10.1002/pro.3137
New visible and selective DNA staining method in gels with tetrazolium salts.
Aaron J. Paredes, Tatiana Naranjo-Palma, Hilda M. Alfaro-Valdés, Andrés Barriga, Jorge Babul, Christian A.M. Wilson. Analytical Biochemistry: Methods in the Biological Sciences. 517 (2017), 31-35, 2017. DOI: 10.1016/j.ab.2016.11.004
Papers in collaboration
Mechanical Force Activates the Light-Dependent Channels TRP and TRPL in Excised Patches from the Rhabdomere of Drosophila Photoreceptors
Delgado, R., Wilson, C. A., Caballero, L., & Melo, F. Mechanical Force Activates the Light-Dependent Channels TRP and TRPL in Excised Patches from the Rhabdomere of Drosophila Photoreceptors. DOI: 10.2139/ssrn.4591563
Identification of VEGFR2 as the Histatin–1 receptor in endothelial cells. Biochemical Pharmacology
Mateluna, C., Torres, P., Rodriguez–Peña, M., Silva, P., Matthies, D. J., Criollo, A., … & Torres, V. A. (2022). , 115079. DOI: https://doi.org/10.1016/j.bcp.2022.115079
Application of Force to a Syndecan-4 Containing Complex With Thy-1–αVβ3 Integrin Accelerates Neurite Retraction
Francesca Burgos-Bravo, Samuel Martínez-Meza, Andrew F. G.Quest, Christian A. M. Wilson and Lisette Leyton. DOI: https://doi.org/10.3389/fmolb.2020.582257
PKD2/polycystin-2 induces autophagy by forming a complex with BECN1.
Daniel Peña-Oyarzun, Marcelo Rodriguez-Peña, Francesca Burgos-Bravo, Angelo Vergara, Catalina Kretschmar, Cristian Sotomayor-Flores, Cesar A. Ramirez-Sarmiento, Humbert De Smedt, Montserrat Reyes, William Perez, Vicente A. Torres, Eugenia Morselli, Francisco Altamirano, Christian A. M. Wilson, Joseph A. Hill, Sergio Lavandero & Alfredo Criollo. Autophagy 2020. DOI:https://doi.org/10.1080/15548627.2020.1782035
Surface Immunogenic Protein of Streptococcus Group B is an Agonist of Toll-Like Receptors 2 and 4 and a Potential Immune Adjuvant.
Diaz-Dinamarca, D.A.; Manzo, R.A.; Soto, D.A.; Avendaño-Valenzuela, M.J.; Bastias, D.N.; Soto, P.I.; Escobar, D.F.; Vasquez-Saez, V.; Carrión, F.; Pizarro-Ortega, M.S.; Wilson, C.A.M.; Berrios, J.; Kalergis, A.M.; Vasquez, A.E. Vaccines 2020, 8, 29. DOI: 10.3390/vaccines8010029
Structural characterization of the saxitoxin-targeting APTSTX1 aptamer using optical tweezers and molecular dynamics simulations.
Nathalie Casanova-Morales, Nataniel L. Figueroa, Karol Alfaro, Felipe Montenegro, Nelson P. Barrera, J. R. Maze, Christian A. M. Wilson, Pablo Conejeros. PloS ONE. 2019, 14(11) DOI: 10.1371/journal.pone.0222468
Single-molecule measurements of the effect of force on Thy-1/αvβ3-integrin interaction using non-purified proteins. Molecular Biology of the Cell
Burgos-Bravo, F.; Figueroa, N.L.; Casanova-Morales, N.; Quest, A.F.G.; Wilson, C.A.M.*; Leyton, L.* Recomendado para publicar con cambios menores: 05 de Junio de 2017.*co-corresponding author. DOI: 10.1091/mbc.E17-03-0133
Identifying Chaotropic and Kosmotropic Agents by Nanorheology.
Nathalie Casanova-Morales, Zahra Alavi, Christian A.M. Wilson, and Giovanni Zocchi. J. Phys. Chem. B, 2018, 122 (14), pp 3754–3759. DOI: 10.1021/acs.jpcb.7b12782
The Energy Cost of Polypeptide Knot Formation and its Folding Consequences.
Andrés Bustamante, Juan Carlos Sotelo, Daniel G. Guerra, Martin Floor, Christian A.M. Wilson, Carlos Bustamante, Mauricio Baez. Nature Communications. 8(1), 1581, 2017. DOI: 10.1038/s41467-017-01691-1
Pulling on super paramagnetic beads with micro cantilevers: single molecule mechanical assay application
Muñoz, R., Aguilar, F., Wilson, C.A.M., Melo, F. Physical Biology.12 (4), 046011, 2015. DOI: 10.1088/1478-3975/12/4/046011